Is it too early for this?
It is too early, give it a year, Biden's first 100 days were not bad at all. Trump started very dynamic but also a bit confused and not well informed, as usually he looks like a work in progress. We'll start get a feel in 100 days and in a year from now we can assess.
For now, there is no visibility where things will actually go. There are some extremely negative signs such as Riviera of the Middle East, but also some very positive such as where regime-changing industrial complex USAID /NED is seemingly going. Regarding Ukraine it can go either direction but I see as very positive that at least they recognise that they should have some kind of dialogue with Russians or other adversaries.
Rubio's comments about the end of US unipolarity are very promising too, I never thought a "neocon" would say something similar let alone the Secretary of State.
About Canada -Mexico let's see what will happen in the end, it's obviously a bizarre and unnecessary thing to punish Canada. I have some doubts if the tariffs will be applied in the end.
To be frank I didn't expect anything good for Gaza either way, just Trump is blunt as fuck where conventional politicians are careful with optics yet the results are similar.
We need to wait and see.
PS
I think it's delusional to believe that America or any other Empire in the history, for that matter, had friends.
Kissinger has famously said "America has no permanent friends or enemies, only interests" and "it may be dangerous to be America's enemy, but to be America's friend is fatal"
If America helped other countries it was
for their own interest and it paid exponentially with the dominance of dollar and the
consequences that it had to their Imperial dominance.