I love and admire both songs, even if I rarely listen to them since they've been overplayed in my stereo.
Both are accomplished songs lyrically and musically. They are dense in their construction -especially RTT Hills, which in only 3'50" gives you a drum intro, the best Maiden galloping until then, a catchy chorus, a guitar solo not that bad, a kick ass bass kind of solo /bridge and a yeeeah -oh-oh-oh sing along section not at all repetitive /boring even after 25 years.
For all the above reasons, plus the production I admire Run To The Hills.
The Number Of The Beast, which is similarly dense in its construction, I like it even better, notably for the terrific spoken intro, the excellent Bruce vocals, its more accomplished story line and its better guitar solos.
So to answer to your question: no it's not a sacrilege, how it could be. But it's a kind of weird